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RA Technique
The OsteoGram uses the Radiographic
Absorptiometry (RA) method to measure bone mineral
density (BMD). Sites of measurements are the middle
phalangeal bones of the 2nd(index),
3rd(middle) and 4th(ring)
fingers. CompuMed has developed the OsteoGram
to implement the RA technique at the highest precision
possible, in addition it has automated the analysis
process.
- Using standard x-ray equipment, two Posterior-Anterior
(PA) views of the left hand fingers are taken
on one 8"x10" film with an aluminum alloy reference
wedge in each exposure
- The developed film is scanned at high resolution,
or in the case of a digital system, the image
is imported. The two exposures are automatically
cropped to be exported to the analysis software
- Elements of interest (the three middle phalangeal
bones and the aluminum wedge) are automatically
identified and their contours highlighted
- X-ray related variations, soft tissue absorption
and small errors in subject positioning are
corrected
- For each phalange, the aluminum wedge is referenced
to measure bone mass in every pixel inside the
automatically detected contour. Then, one average
bone mass is calculated per bone
- For each phalange, bone volume is calculated
from bone contour and bone length by superimposing
the cylindrically shaped one-pixel-thick cross
sections
- BMD is calculated in arbitrary units for the
three bones in each exposure (six total)
- BMD results are cross-checked between the
two exposures. Variations in BMD results higher
than the precision error would invoke an error
message (to verify the validity of the scanned
x-ray and re-take the x-ray if necessary)
- The overall average BMD index is considered,
normative databases are referenced to calculate
t-score and z-score
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